Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms
نویسندگان
چکیده
منابع مشابه
Translational Regulatory Mechanisms in Persistent Forms of Synaptic Plasticity
Memory and synaptic plasticity exhibit distinct temporal phases, with long-lasting forms distinguished by their dependence on macromolecular synthesis. Prevailing models for the molecular mechanisms underlying long-lasting synaptic plasticity have largely focused on transcriptional regulation. However, a growing body of evidence now supports a crucial role for neuronal activity-dependent mRNA t...
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Brain is a sophisticated information processing and storage system with capabilities unmatched by any manmade computers. Neurons, the primary building blocks of the brain are structurally and functionally specialized to do these functions. The neuronal membrane is equipped with several types of ion channel and ion pump proteins which enable it to conduct nerve impulses in the form of electroche...
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We propose a model of intrinsic plasticity for a continuous activation model neuron based on information theory. We then show how intrinsic and synaptic plasticity mechanisms interact and allow the neuron to discover heavy-tailed directions in the input. We also demonstrate that intrinsic plasticity may be an alternative explanation for the sliding threshold postulated in the BCM theory of syna...
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context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2007
ISSN: 0893-133X,1740-634X
DOI: 10.1038/sj.npp.1301559